FLT3 Protein
Quick Overview for FLT3 Protein (ABIN935355)
Target
See all FLT3 ProteinsProtein Type
Origin
Source
Purity
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Characteristics
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Purified recombinant Mouse FIt3 Ligand protein
Expression System: E.coli
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Fms-Related tyrosine Kinase 3 (FLT3) (AA 27-541) protein (Fc Tag)
FLT3 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Fms-Related tyrosine Kinase 3 (FLT3) (AA 28-541) protein (Fc Tag)FLT3 Origin: Cynomolgus Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Fms-Related tyrosine Kinase 3 (FLT3) (AA 28-544) protein (Fc Tag)FLT3 Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Fms-Related tyrosine Kinase 3 (FLT3) (AA 27-543) protein (Fc-His Tag)FLT3 Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. ELISA
Fms-Related tyrosine Kinase 3 (FLT3) protein (His tag)FLT3 Origin: Mouse Host: HEK-293 Cells Recombinant > 75 % as determined by SDS-PAGE
Fms-Related tyrosine Kinase 3 (FLT3) (AA 27-543) (Active) protein (Fc Tag)FLT3 Origin: Human Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Reconstitute in water to a concentration of 0.1-1.0 mg/mL.
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Buffer
- Lyophilized from 10 mM Na3PO4, pH 7.8.
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- RT/-20 °C
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- FLT3 (Fms-Related tyrosine Kinase 3 (FLT3))
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Alternative Name
- FLT3
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Background
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FLT3 is a receptor tyrosine kinase with important roles in hematopoietic stem/progenitor cell survival and proliferation. It is mutated in about 1/3 of acute myeloid leukemia (AML) patients, either by internal tandem duplications (ITD) of the juxtamembrane domain or by point mutations usually involving the kinase domain (kDa).
Alternative Names: Flt3, FLT3 protein, Flt-3, Flt-3 ligand, Fms-related tyrosine kinase 3 ligand protein, Flt-3 protein, Flt 3, Flt-3 protein, Flt 3 protein -
Pathways
- RTK Signaling
Target
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