Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

CD27 Protein (AA 21-192) (Fc Tag)

CD27 Origin: Human Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Catalog No. ABIN2180735
  • Target See all CD27 Proteins
    CD27 (CD27 Molecule (CD27))
    Protein Type
    Recombinant
    Biological Activity
    Active
    Protein Characteristics
    AA 21-192
    Origin
    • 26
    • 9
    • 3
    • 3
    • 1
    Human
    Source
    • 20
    • 7
    • 6
    • 2
    • 2
    • 2
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This CD27 protein is labelled with Fc Tag.
    Sequence
    AA 21-192
    Characteristics
    This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 45.9 kDa. The protein migrates as 45-65 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
    Purity
    >95 % as determined by SDS-PAGE.
    Sterility
    0.22 μm filtered
    Endotoxin Level
    Less than 1.0 EU per μg by the LAL method.
    Top Product
    Discover our top product CD27 Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    50 mM Tris, 100 mM Glycine, pH 7.5
    Handling Advice
    Please avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C), After reconstitution under sterile conditions for 3 months (-70 °C).
  • Target
    CD27 (CD27 Molecule (CD27))
    Alternative Name
    CD27 (CD27 Products)
    Background
    CD Antigen CD27 is also known as Tumor necrosis factor receptor superfamily member 7 (TNFRSF7), which belongs to TNF-receptor superfamily. CD27 / TNFRSF7 is found in most T-lymphocytes. CD27 / TNFRSF7 is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-κB and MAPK8/JNK. CD27 has been shown to interact with SIVA1, TRAF2 and TRAF3.
    Molecular Weight
    45.9 kDa
    NCBI Accession
    NP_001233
    Pathways
    Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints
You are here:
Support