CD58 Protein (CD58) (His tag)
Quick Overview for CD58 Protein (CD58) (His tag) (ABIN2566429)
Target
See all CD58 ProteinsProtein Type
Biological Activity
Origin
Source
Application
Purity
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Purification tag / Conjugate
- This CD58 protein is labelled with His tag.
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Characteristics
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Measured in a cell proliferation assay using human CD3+ T cells in the presence of anti-CD3. The ED50 for this effect is typically 1 - 5 μg/mL in the presence of anti-CD3 immobilized at 25 ng/mL.
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CD58 (CD58) (AA 29-215) protein (Fc Tag)
CD58 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
CD58 (CD58) (AA 1-240) protein (GST tag)CD58 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
CD58 (CD58) (AA 29-215) protein (His tag)CD58 Origin: Human Host: Baculovirus infected Insect Cells Recombinant > 95% by SDS-PAGE SDS
CD58 (CD58) (AA 29-215) protein (His tag)CD58 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % by SDS - PAGE SDS
CD58 (CD58) (AA 29-215) protein (His tag)CD58 Origin: Human Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE.
CD58 (CD58) (AA 29-215) (Active) protein (Fc Tag)CD58 Origin: Human Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
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Application Notes
- This recombinant protein can be used for WB. For research use only.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- PBS, pH 7.4
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Storage
- -80 °C,-20 °C
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Storage Comment
- Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C. Avoid repeated freeze-thaw cycles.
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- CD58
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Alternative Name
- CD58
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Background
- CD antigen CD58 is also known as Lymphocyte function-associated antigen 3 (LFA-3). CD58 is a cell adhesion molecule expressed on Antigen Presenting Cells (APC), particularly macrophages. CD58 /LFA3 is ligand of the T-lymphocyte CD2 glycoprotein, which binds to CD2 (LFA-2) [3] on T cells and is important in strengthening the adhesion between the T cells and Professional Antigen Presenting Cells. In addition, the LFA-3/CD2 interaction may prime response by both the CD2+ and LFA-3+ cells. Polymorphisms in the CD58 gene are associated with increased risk for multiple sclerosis.
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Molecular Weight
- 22.3 kDa
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Gene ID
- 965
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UniProt
- P19256
Target
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