CD58 Protein (CD58) (AA 29-215) (Fc Tag)

Catalog No. ABIN7319528

Recombinant CD58 protein expressed in HEK-293 Cells.

Quick Overview for CD58 Protein (CD58) (AA 29-215) (Fc Tag) (ABIN7319528)

Target: CD58

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Purity: > 95 % as determined by reducing SDS-PAGE.

Product Details

Protein Characteristics: AA 29-215

Purification tag / Conjugate: This CD58 protein is labelled with Fc Tag.

Purpose: Recombinant Human LFA-3/CD58 Protein (Fc Tag)

Sequence: Phe29-Arg215

Characteristics: Recombinant Human CD58 is produced by our Mammalian expression system and the target gene encoding Phe29-Arg215 is expressed with a Fc tag at the C-terminus.

Sterility: 0.2 μm filtered

Endotoxin Level: < 1.0 EU per μg of the protein as determined by the LAL method.

Biological Activity Comment: Not validated for activity

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Expiry Date: 12 months

Target Details

Target: CD58

Alternative Name: LFA-3/CD58

Background: Ag3,CD58,CD58 antigen,LFA3,Lymphocyte Function-Associated Antigen 3,Surface Glycoprotein LFA-3,Lymphocyte function-associated antigen 3 (LFA-3/CD58) is a single-pass type I membrane protein. CD58 is widely expressed on hematopoietic and non-hematopoietic human tissue and has been found on leukocytes, erythrocytes, endothelial cells, epithelial cells and fibroblasts of human origin. It is a Ligand of the T-lymphocyte CD2 glycoprotein. This interaction is important in mediating thymocyte interactions with thymic epithelial cells, antigen-independent and -dependent interactions of T-lymphocytes with target cells and antigen-presenting cells and the T-lymphocyte rosetting with erythrocytes. In addition, the LFA-3/CD2 interaction may prime response by both the CD2+ and LFA-3+ cells.

Molecular Weight:

Calculated MW: 48.6 kDa

Observed MW: 60-90 kDa

Gene ID: 965

UniProt: P19256