2B4 Protein (His tag)
Quick Overview for 2B4 Protein (His tag) (ABIN2566940)
Target
See all 2B4 (CD244) ProteinsProtein Type
Biological Activity
Origin
Source
Application
Purity
-
-
Purification tag / Conjugate
- This 2B4 protein is labelled with His tag.
-
Characteristics
-
Measured by its binding ability in a functional ELISA. Immobilized rh CD244 / 2B4 at 2 μg/mL (100 μL/well ) can bind human CD48. The EC50 of human CD48 is 0. 39 μg/mL.
-
-
Want other Options for this Protein ?
!Discover Our Predefined Custom Proteins and Custom Protein Services!Your project requires further customization? Contact us and discover our custom protein solutions
-
-
-
Application Notes
- This recombinant protein can be used for WB, ELISA. For research use only.
-
Restrictions
- For Research Use only
-
-
-
Format
- Lyophilized
-
Buffer
- PBS, pH 7.4
-
Storage
- -80 °C,-20 °C
-
Storage Comment
- Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C. Avoid repeated freeze-thaw cycles.
-
-
- 2B4 (CD244) (Natural Killer Cell Receptor 2B4 (CD244))
-
Alternative Name
- SLAMF 4
-
Background
- Natural killer cell receptor 2B4 is also known as NK cell type I receptor protein 2B4 (NKR2B4 or h2B4), SLAM family member 4 (SLAMF4), Signaling lymphocytic activation molecule 4, CD antigen CD244. NKR2B4 / CD244 contains two Ig-like (immunoglobulin-like) domains. CD244 is expressed in spleen, PBL, followed by lung, liver, testis and small intestine. CD244 interacts with CD48. Following phosphorylation, CD244 is able to recruit PTPN11/SHP-2 and SH2D1A/SAP. SLAMF4 modulate other receptor-ligand interactions to enhance leukocyte activation. CD244/2B4 is the only heterophilic receptor of SLAM family.
-
Molecular Weight
- 23.1 kDa
-
Gene ID
- 51744
-
NCBI Accession
- NP_057466
-
UniProt
- Q9BZW8
Target
-