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2B4 Protein (His tag)

Recombinant 2B4 protein expressed in HEK-293 Cells.
Catalog No. ABIN2566940
$742.50
Plus shipping costs $50.00
100 μg
Shipping to: United States
Delivery in 2 to 4 Business Days

Quick Overview for 2B4 Protein (His tag) (ABIN2566940)

Target

See all 2B4 (CD244) Proteins
2B4 (CD244) (Natural Killer Cell Receptor 2B4 (CD244))

Protein Type

Recombinant

Biological Activity

Active

Origin

  • 22
  • 7
  • 3
Human

Source

  • 13
  • 7
  • 5
  • 2
  • 2
  • 1
  • 1
  • 1
HEK-293 Cells

Application

Western Blotting (WB), ELISA

Purity

>95 % as determined by SDS-PAGE.
  • Purification tag / Conjugate

    This 2B4 protein is labelled with His tag.

    Characteristics

    Measured by its binding ability in a functional ELISA. Immobilized rh CD244 / 2B4 at 2 μg/mL (100 μL/well ) can bind human CD48. The EC50 of human CD48 is 0. 39 μg/mL.

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  • Application Notes

    This recombinant protein can be used for WB, ELISA. For research use only.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Buffer

    PBS, pH 7.4

    Storage

    -80 °C,-20 °C

    Storage Comment

    Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C. Avoid repeated freeze-thaw cycles.
  • Target

    2B4 (CD244) (Natural Killer Cell Receptor 2B4 (CD244))

    Alternative Name

    SLAMF 4

    Background

    Natural killer cell receptor 2B4 is also known as NK cell type I receptor protein 2B4 (NKR2B4 or h2B4), SLAM family member 4 (SLAMF4), Signaling lymphocytic activation molecule 4, CD antigen CD244. NKR2B4 / CD244 contains two Ig-like (immunoglobulin-like) domains. CD244 is expressed in spleen, PBL, followed by lung, liver, testis and small intestine. CD244 interacts with CD48. Following phosphorylation, CD244 is able to recruit PTPN11/SHP-2 and SH2D1A/SAP. SLAMF4 modulate other receptor-ligand interactions to enhance leukocyte activation. CD244/2B4 is the only heterophilic receptor of SLAM family.

    Molecular Weight

    23.1 kDa

    Gene ID

    51744

    NCBI Accession

    NP_057466

    UniProt

    Q9BZW8
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