GNMT Protein (Myc-DYKDDDDK Tag)

Catalog No. ABIN2712294

This Recombinant GNMT protein is produced in HEK-293 Cells.

Quick Overview for GNMT Protein (Myc-DYKDDDDK Tag) (ABIN2712294)

Target: GNMT (Glycine N-Methyltransferase (GNMT))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Application: Antibody Production (AbP), Standard (STD)

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Product Details

Purification tag / Conjugate: This GNMT protein is labelled with Myc-DYKDDDDK Tag.

Characteristics:

• Recombinant human GNMT protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: GNMT (Glycine N-Methyltransferase (GNMT))

Alternative Name: Gnmt

Background: The protein encoded by this gene is an enzyme that catalyzes the conversion of S-adenosyl-L-methionine (along with glycine) to S-adenosyl-L-homocysteine and sarcosine. This protein is found in the cytoplasm and acts as a homotetramer. Defects in this gene are a cause of GNMT deficiency (hypermethioninemia). Alternative splicing results in multiple transcript variants. Naturally occurring readthrough transcription occurs between the upstream CNPY3 (canopy FGF signaling regulator 3) gene and this gene and is represented with GeneID:107080644.

Molecular Weight: 32.6 kDa

NCBI Accession: NP_061833

Pathways: Cellular Glucan Metabolic Process, Regulation of Carbohydrate Metabolic Process