GNMT Protein (His tag)
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- Target See all GNMT Proteins
- GNMT (Glycine N-Methyltransferase (GNMT))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This GNMT protein is labelled with His tag.
- Purpose
- Recombinant Human GNMT Protein (His Tag)
- Sequence
- Met 1-Asg294
- Characteristics
- Recombinant Human Glycine N-Methyltransferase is produced by our E.coli expression system and the target gene encoding Met1-Asg294 is expressed with a 6His tag at the N-terminus.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product GNMT Protein
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Glycine N-Methyltransferase (GNMT) (AA 1-100) protein (GST tag)
GNMT Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Glycine N-Methyltransferase (GNMT) (AA 1-295) protein (His tag)GNMT Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % by SDS - PAGE SDS
Glycine N-Methyltransferase (GNMT) (AA 1-295) protein (GST tag)GNMT Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Glycine N-Methyltransferase (GNMT) (AA 2-295) protein (His tag)Crystallography grade GNMT Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Glycine N-Methyltransferase (GNMT) (AA 2-293) protein (His tag)Crystallography grade GNMT Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Glycine N-Methyltransferase (GNMT) (AA 1-295) (Active) protein (His tag)GNMT Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % by SDS - PAGE SDS Active
Glycine N-Methyltransferase (GNMT) protein (Myc-DYKDDDDK Tag)GNMT Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Restrictions
- For Research Use only
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- Format
- Frozen, Liquid
- Buffer
- Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl, 150 mM NaCl, pH 8.0.
- Storage
- -20 °C
- Storage Comment
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- Target
- GNMT (Glycine N-Methyltransferase (GNMT))
- Alternative Name
- GNMT (GNMT Products)
- Synonyms
- glycine N-methyltransferase Protein, CpipJ_CPIJ015956 Protein, Gnmt Protein, GNMT Protein
- Background
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Background: Glycine N-Methyltransferase (GNMT) is a tetrameric cytosolic protein. GNMT catalyzes the synthesis of N-methylglycine from glycine using S-adenosylmethionine (AdoMet) as the methyl donor. It can affects DNA methylation by regulating the ratio of S-adenosylmethionine to S-adenosylhomocystine, playing an important role in maintaining normal AdoMet levels. GNMT is highly expressed in liver. As a major folate-binding protein, GNMT takes part in the detoxification pathway. Defects in GNMT are the cause of hypermethioninemia. the patients with this deficiency are mild hepatomegaly and chronic elevation of serum transaminases.
Synonym: Glycine N-Methyltransferase, GNMT
- Molecular Weight
- 34.9 kDa
- UniProt
- Q14749
- Pathways
- Cellular Glucan Metabolic Process, Regulation of Carbohydrate Metabolic Process
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