MAPT Protein (Transcript Variant 6) (His tag)

Catalog No. ABIN2712319

This Recombinant MAPT protein is expressed in Escherichia coli (E. coli).

Quick Overview for MAPT Protein (Transcript Variant 6) (His tag) (ABIN2712319)

Target: MAPT (Microtubule-Associated Protein tau (MAPT))

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Application: Antibody Production (AbP), Standard (STD)

Purity: > 95 % as determined by SDS-PAGE and Coomassie blue staining

Product Details

Protein Characteristics: Transcript Variant 6

Purification tag / Conjugate: This MAPT protein is labelled with His tag.

Characteristics:

• Recombinant human MAPT / TAU (transcript variant 6) protein expressed in E. coli.
• Produced with end-sequenced ORF clone

Endotoxin Level: < 0.1 EU per μg protein as determined by LAL test

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the N-terminal.

Restrictions: For Research Use only

Handling

Buffer: Lyophilized from a 0.2 μM filtered solution of 20 mM Phosphate buffer, 150 mM NaCl, pH 7.4. Stable for at least 6 months from date of receipt under proper storage and handling conditions.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: MAPT (Microtubule-Associated Protein tau (MAPT))

Alternative Name: Mapt,tau

Background: This gene encodes the microtubule-associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimer&aposs disease, Pick&aposs disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy.

Molecular Weight: 15.4 kDa

NCBI Accession: NP_001116538

Pathways: MAPK Signaling, Microtubule Dynamics, M Phase, Regulation of Cell Size