MAPT Protein (AA 1-383) (His tag)
Quick Overview for MAPT Protein (AA 1-383) (His tag) (ABIN7279235)
Target
See all MAPT ProteinsProtein Type
Origin
Source
Application
Purity
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Protein Characteristics
- AA 1-383
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Purification tag / Conjugate
- This MAPT protein is labelled with His tag.
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Sequence
- MAEPRQEFEV MEDHAGTYGL GDRKDQGGYT MHQDQEGDTD AGLKAEEAGI GDTPSLEDEA AGHVTQARMV SKSKDGTGSD DKKAKGADGK TKIATPRGAA PPGQKGQANA TRIPAKTPPA PKTPPSSGEP PKSGDRSGYS SPGSPGTPGS RSRTPSLPTP PTREPKKVAV VRTPPKSPSS AKSRLQTAPV PMPDLKNVKS KIGSTENLKH QPGGGKVQII NKKLDLSNVQ SKCGSKDNIK HVPGGGSVQI VYKPVDLSKV TSKCGSLGNI HHKPGGGQVE VKSEKLDFKD RVQSKIGSLD NITHVPGGGN KKIETHKLTF RENAKAKTDH GAEIVYKSPV VSGDTSPRHL SNVSSTGSID MVDSPQLATL ADEVSASLAK QGL
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Characteristics
- TAU, 1-383aa, Human, His tag, E.coli
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Purification
- > 85% by SDS-PAGE
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Microtubule-Associated Protein tau (MAPT) (AA 1-381) protein (His tag)
MAPT Origin: Human Host: Escherichia coli (E. coli) Recombinant > 85 % SDS
Microtubule-Associated Protein tau (MAPT) (AA 1-352) protein (His tag)MAPT Origin: Human Host: Escherichia coli (E. coli) Recombinant > 85 % SDS
Microtubule-Associated Protein tau (MAPT) (AA 2-752), (full length) protein (His tag)MAPT Origin: Rat Host: Yeast Recombinant > 90 % ELISA
Microtubule-Associated Protein tau (MAPT) (Transcript Variant 6) protein (His tag)MAPT Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- 20 mM Tris-HCl buffer ( pH 8.0) containing 10 % glycerol, 0.1M NaCl
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Handling Advice
- Avoid repeated freezing and thawing cycles
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Storage
- 4 °C,-20 °C,-80 °C
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Storage Comment
- Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
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- MAPT (Microtubule-Associated Protein tau (MAPT))
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Alternative Name
- MAPT
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Background
- Tau, also known as microtubule-associated protein tau (MAPT), is a protein that stabilizes microtubules. It is abundant in neurons in the central nervous system and is less common elsewhere. When this protein is defective, and no longer stabilizes microtubules properly, it can result in dementias, such as Alzheimer's disease. Recombinant human Tau protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.
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Molecular Weight
- 42.1 kDa (403aa) confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)
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NCBI Accession
- NP_058518
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Pathways
- MAPK Signaling, Microtubule Dynamics, M Phase, Regulation of Cell Size
Target
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