CPE Protein (Myc-DYKDDDDK Tag)

Catalog No. ABIN2713154

Recombinant CPE protein expressed in HEK-293 Cells.

Quick Overview for CPE Protein (Myc-DYKDDDDK Tag) (ABIN2713154)

Target: CPE (Carboxypeptidase E (CPE))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Application: Antibody Production (AbP), Standard (STD)

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Product Details

Purification tag / Conjugate: This CPE protein is labelled with Myc-DYKDDDDK Tag.

Characteristics:

• Recombinant human Carboxypeptidase E protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: CPE (Carboxypeptidase E (CPE))

Alternative Name: Carboxypeptidase E

Background: This gene encodes a member of the M14 family of metallocarboxypeptidases. The encoded preproprotein is proteolytically processed to generate the mature peptidase. This peripheral membrane protein cleaves C-terminal amino acid residues and is involved in the biosynthesis of peptide hormones and neurotransmitters, including insulin. This protein may also function independently of its peptidase activity, as a neurotrophic factor that promotes neuronal survival, and as a sorting receptor that binds to regulated secretory pathway proteins, including prohormones. Mutations in this gene are implicated in type 2 diabetes.

Molecular Weight: 50.8 kDa

NCBI Accession: NP_001864

Pathways: Peptide Hormone Metabolism, Synaptic Membrane