Cardiotrophin 1 Protein (CTF1) (Transcript Variant 1)
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- Target See all Cardiotrophin 1 (CTF1) Proteins
- Cardiotrophin 1 (CTF1)
- Protein Type
- Recombinant
- Biological Activity
- Active
- Protein Characteristics
- Transcript Variant 1
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Application
- Functional Studies (Func), Antibody Production (AbP), Protein Interaction (PI), Standard (STD)
- Specificity
- Optimal preservation of protein structure, post-translational modifications and functions.
- Characteristics
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- Recombinant human Cardiotrophin-1 (transcript variant 1) protein expressed in E. coli.
- Produced with end-sequenced ORF clone
- Tested for bioactivity.
- Purity
- > 95 % as determined by SDS-PAGE and Coomassie blue staining
- Endotoxin Level
- Endotoxin level is <0.1 ng/μg of protein (<1EU/μg).
- Biological Activity Comment
- ED50 as determined by the dose-dependent proliferation of TF-1 cells was
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- Discover our top product CTF1 Protein
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Cardiotrophin 1 (CTF1) (Active) protein
CTF1 Origin: Human Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS-PAGE Func Active
Cardiotrophin 1 (CTF1) (AA 1-201) protein (GST tag)CTF1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Cardiotrophin 1 (CTF1) (AA 1-201) protein (His tag)Crystallography grade CTF1 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays
Protein-protein interaction
In vitro biochemical assays and cell-based functional assays - Restrictions
- For Research Use only
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- Buffer
- Lyophilized from a 0.2 μM filtered solution of 20 mM phosphate buffer,100 mM NaCl, pH 7.2
- Handling Advice
- Resuspend the protein in the desired concentration in proper buffer
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- Cardiotrophin 1 (CTF1)
- Alternative Name
- Cardiotrophin-1 (CTF1 Products)
- Synonyms
- CTF1 Protein, ct1 Protein, ct-1 Protein, ctf2 Protein, CT-1 Protein, CT1 Protein, cardiotrophin 1 Protein, cardiotrophin-1 Protein, CTF1 Protein, ctf1 Protein, Ctf1 Protein, LOC100736818 Protein
- Background
- The protein encoded by this gene is a secreted cytokine that induces cardiac myocyte hypertrophy in vitro. It has been shown to bind and activate the ILST/gp130 receoptor. Two transcript variants encoding different isoforms have been found for this gene.
- Molecular Weight
- 21.1 kDa
- NCBI Accession
- NP_001321
- Pathways
- JAK-STAT Signaling
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