Caspase 1 Protein (CASP1) (Myc-DYKDDDDK Tag)
Quick Overview for Caspase 1 Protein (CASP1) (Myc-DYKDDDDK Tag) (ABIN2713201)
Target
See all Caspase 1 (CASP1) ProteinsProtein Type
Origin
Source
Application
Purity
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Purification tag / Conjugate
- This Caspase 1 protein is labelled with Myc-DYKDDDDK Tag.
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Characteristics
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- Recombinant human Caspase-1 (transcript variant delta) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Caspase 1 (CASP1) (AA 120-269) protein (His tag)
CASP1 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
Caspase 1 (CASP1) (AA 120-404) protein (His-IF2DI Tag)CASP1 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
Caspase 1 (CASP1) (AA 1-311) protein (GST tag)CASP1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Caspase 1 (CASP1) (AA 1-100) protein (GST tag)CASP1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Caspase 1 (CASP1) (AA 120-269), (partial) protein (GST tag)CASP1 Origin: Human Host: Escherichia coli (E. coli) Recombinant 90 % ELISA
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Caspase 1 (CASP1)
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Alternative Name
- Caspase-1
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Background
- This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce 2 subunits, large and small, that dimerize to form the active enzyme. This gene was identified by its ability to proteolytically cleave and activate the inactive precursor of interleukin-1, a cytokine involved in the processes such as inflammation, septic shock, and wound healing. This gene has been shown to induce cell apoptosis and may function in various developmental stages. Studies of a similar gene in mouse suggest a role in the pathogenesis of Huntington disease. Alternative splicing results in transcript variants encoding distinct isoforms.
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Molecular Weight
- 29.6 kDa
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NCBI Accession
- NP_150636
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Pathways
- Apoptosis, Interferon-gamma Pathway, Positive Regulation of Endopeptidase Activity, Inflammasome
Target
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