Caveolin 2 Protein (CAV2) (Transcript Variant 1) (Myc-DYKDDDDK Tag)
Quick Overview for Caveolin 2 Protein (CAV2) (Transcript Variant 1) (Myc-DYKDDDDK Tag) (ABIN2713245)
Target
See all Caveolin 2 (CAV2) ProteinsProtein Type
Origin
Source
Application
Purity
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Protein Characteristics
- Transcript Variant 1
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Purification tag / Conjugate
- This Caveolin 2 protein is labelled with Myc-DYKDDDDK Tag.
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Characteristics
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- Recombinant human Caveolin-2 (transcript variant 1) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Caveolin 2 (CAV2)
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Alternative Name
- Caveolin-2
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Background
- The protein encoded by this gene is a major component of the inner surface of caveolae, small invaginations of the plasma membrane, and is involved in essential cellular functions, including signal transduction, lipid metabolism, cellular growth control and apoptosis. This protein may function as a tumor suppressor. This gene and related family member (CAV1) are located next to each other on chromosome 7, and express colocalizing proteins that form a stable hetero-oligomeric complex. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. Additional isoforms resulting from the use of alternate in-frame translation initiation codons have also been described, and shown to have preferential localization in the cell (PMID:11238462).
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Molecular Weight
- 18.1 kDa
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NCBI Accession
- NP_001224
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Pathways
- Regulation of G-Protein Coupled Receptor Protein Signaling, Skeletal Muscle Fiber Development
Target
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