IL5RA Protein (Transcript Variant 3) (Myc-DYKDDDDK Tag)
Quick Overview for IL5RA Protein (Transcript Variant 3) (Myc-DYKDDDDK Tag) (ABIN2713397)
Target
See all IL5RA ProteinsProtein Type
Origin
Source
Application
Purity
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Protein Characteristics
- Transcript Variant 3
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Purification tag / Conjugate
- This IL5RA protein is labelled with Myc-DYKDDDDK Tag.
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Characteristics
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- Recombinant human CD125 / IL5RA (transcript variant 3) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- IL5RA (Interleukin 5 Receptor, alpha (IL5RA))
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Alternative Name
- Cd125,il5ra
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Background
- The protein encoded by this gene is an interleukin 5 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL5 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL5. This protein has been found to interact with syndecan binding protein (syntenin), which is required for IL5 mediated activation of the transcription factor SOX4. Several alternatively spliced transcript variants encoding four distinct isoforms have been reported.
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Molecular Weight
- 37.8 kDa
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NCBI Accession
- NP_783852
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Pathways
- JAK-STAT Signaling
Target
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