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IL5RA Protein (Transcript Variant 3) (Myc-DYKDDDDK Tag)

Recombinant IL5RA protein expressed in HEK-293 Cells.
Catalog No. ABIN2713397
$956.40
Plus shipping costs $50.00, if applicable $20.00 dry ice
20 μg
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Quick Overview for IL5RA Protein (Transcript Variant 3) (Myc-DYKDDDDK Tag) (ABIN2713397)

Target

See all IL5RA Proteins
IL5RA (Interleukin 5 Receptor, alpha (IL5RA))

Protein Type

Recombinant

Origin

  • 17
  • 8
Human

Source

  • 9
  • 4
  • 4
  • 3
  • 2
  • 2
  • 1
HEK-293 Cells

Application

Antibody Production (AbP), Standard (STD)

Purity

> 80 % as determined by SDS-PAGE and Coomassie blue staining
  • Protein Characteristics

    Transcript Variant 3

    Purification tag / Conjugate

    This IL5RA protein is labelled with Myc-DYKDDDDK Tag.

    Characteristics

    • Recombinant human CD125 / IL5RA (transcript variant 3) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
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  • Application Notes

    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays

    Comment

    The tag is located at the C-terminal.

    Restrictions

    For Research Use only
  • Concentration

    50 μg/mL

    Buffer

    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

    Storage

    -80 °C

    Storage Comment

    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target

    IL5RA (Interleukin 5 Receptor, alpha (IL5RA))

    Alternative Name

    Cd125,il5ra

    Background

    The protein encoded by this gene is an interleukin 5 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL5 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL5. This protein has been found to interact with syndecan binding protein (syntenin), which is required for IL5 mediated activation of the transcription factor SOX4. Several alternatively spliced transcript variants encoding four distinct isoforms have been reported.

    Molecular Weight

    37.8 kDa

    NCBI Accession

    NP_783852

    Pathways

    JAK-STAT Signaling
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