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Poliovirus Receptor Protein (PVR) (Transcript Variant 2)

This Recombinant Poliovirus Receptor protein is produced in HEK-293 Cells.
Catalog No. ABIN2713446

Quick Overview for Poliovirus Receptor Protein (PVR) (Transcript Variant 2) (ABIN2713446)

Target

See all Poliovirus Receptor (PVR) Proteins
Poliovirus Receptor (PVR)

Protein Type

Recombinant

Origin

  • 26
  • 7
  • 3
  • 2
  • 1
Human

Source

  • 24
  • 5
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
HEK-293 Cells

Application

Antibody Production (AbP), Standard (STD)

Purity

> 95 % as determined by SDS-PAGE and Coomassie blue staining
  • Protein Characteristics

    Transcript Variant 2

    Characteristics

    • Recombinant human CD155 / PVR (transcript variant 2) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone

    Endotoxin Level

    < 0.1 EU per μg protein as determined by LAL test
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  • Application Notes

    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays

    Restrictions

    For Research Use only
  • Concentration

    50 μg/mL

    Buffer

    20 mM Phosphate buffer, 150 mM NaCl, pH 7.4. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions.

    Storage

    -80 °C

    Storage Comment

    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target

    Poliovirus Receptor (PVR)

    Alternative Name

    Cd155,pvr

    Background

    The protein encoded by this gene is a transmembrane glycoprotein belonging to the immunoglobulin superfamily. The external domain mediates cell attachment to the extracellular matrix molecule vitronectin, while its intracellular domain interacts with the dynein light chain Tctex-1/DYNLT1. The gene is specific to the primate lineage, and serves as a cellular receptor for poliovirus in the first step of poliovirus replication. Multiple transcript variants encoding different isoforms have been found for this gene.

    Molecular Weight

    36.1 kDa

    NCBI Accession

    NP_001129240

    Pathways

    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cell-Cell Junction Organization, Cancer Immune Checkpoints, SARS-CoV-2 Protein Interactome
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