DDR1 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)
Quick Overview for DDR1 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag) (ABIN2713452)
Target
See all DDR1 ProteinsProtein Type
Origin
Source
Application
Purity
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Protein Characteristics
- Transcript Variant 1
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Purification tag / Conjugate
- This DDR1 protein is labelled with Myc-DYKDDDDK Tag.
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Characteristics
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- Recombinant human CD167a / DDR1 (transcript variant 1) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Discoidin Domain Receptor tyrosine Kinase 1 (DDR1) (AA 21-417) (Active) protein (His tag)
DDR1 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Discoidin Domain Receptor tyrosine Kinase 1 (DDR1) (AA 22-415) (Active) protein (His tag)DDR1 Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Discoidin Domain Receptor tyrosine Kinase 1 (DDR1) (AA 278-377) protein (GST tag)DDR1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Discoidin Domain Receptor tyrosine Kinase 1 (DDR1) (AA 22-876) protein (GST tag)DDR1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Discoidin Domain Receptor tyrosine Kinase 1 (DDR1) (Active) protein (GST tag,His tag)DDR1 Origin: Mouse Host: Baculovirus infected Insect Cells Recombinant > 95 % as determined by SDS-PAGE Active
Discoidin Domain Receptor tyrosine Kinase 1 (DDR1) protein (Fc Tag)DDR1 Origin: Rat Host: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE
Discoidin Domain Receptor tyrosine Kinase 1 (DDR1) protein (His tag)DDR1 Origin: Rat Host: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE
Discoidin Domain Receptor tyrosine Kinase 1 (DDR1) (Active) protein (GST tag,His tag)DDR1 Origin: Human Host: Baculovirus infected Insect Cells Recombinant > 89 % as determined by reducing SDS-PAGE. Active
Discoidin Domain Receptor tyrosine Kinase 1 (DDR1) protein (Fc Tag)DDR1 Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE
Discoidin Domain Receptor tyrosine Kinase 1 (DDR1) protein (His tag)DDR1 Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- DDR1 (Discoidin Domain Receptor tyrosine Kinase 1 (DDR1))
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Alternative Name
- Cd167a,ddr1
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Background
- Receptor tyrosine kinases play a key role in the communication of cells with their microenvironment. These kinases are involved in the regulation of cell growth, differentiation and metabolism. The protein encoded by this gene belongs to a subfamily of tyrosine kinase receptors with homology to Dictyostelium discoideum protein discoidin I in their extracellular domain, and that are activated by various types of collagen. Expression of this protein is restricted to epithelial cells, particularly in the kidney, lung, gastrointestinal tract, and brain. In addition, it has been shown to be significantly overexpressed in several human tumors. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
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Molecular Weight
- 100.9 kDa
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NCBI Accession
- NP_054699
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Pathways
- RTK Signaling, Smooth Muscle Cell Migration
Target
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