FGFR3 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)
Quick Overview for FGFR3 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag) (ABIN2713668)
Target
See all FGFR3 ProteinsProtein Type
Origin
Source
Application
Purity
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Protein Characteristics
- Transcript Variant 1
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Purification tag / Conjugate
- This FGFR3 protein is labelled with Myc-DYKDDDDK Tag.
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Characteristics
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- Recombinant human CD333 / FGFR3 (transcript variant 1) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Fibroblast Growth Factor Receptor 3 (FGFR3) (AA 23-375) protein (His tag)
FGFR3 Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining. AM, ADA, IA, ScA
Fibroblast Growth Factor Receptor 3 (FGFR3) (AA 23-320) protein (His tag)FGFR3 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
Fibroblast Growth Factor Receptor 3 (FGFR3) protein (Fc Tag)FGFR3 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
Fibroblast Growth Factor Receptor 3 (FGFR3) (Active) protein (His tag)FGFR3 Origin: Mouse Host: HEK-293 Cells Recombinant > 98 % as determined by reducing SDS-PAGE. Active
Fibroblast Growth Factor Receptor 3 (FGFR3) (Active) protein (His-Fc tag)FGFR3 Origin: Mouse Host: HEK-293 Cells Recombinant > 92 % as determined by reducing SDS-PAGE. ELISA Active
Fibroblast Growth Factor Receptor 3 (FGFR3) (AA 27-126) protein (GST tag)FGFR3 Origin: Human Host: Wheat germ Recombinant AP, AA, ELISA, WB
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- FGFR3 (Fibroblast Growth Factor Receptor 3 (FGFR3))
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Alternative Name
- Cd333,fgfr3
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Background
- This gene encodes a member of the fibroblast growth factor receptor (FGFR) family, with its amino acid sequence being highly conserved between members and among divergent species. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein would consist of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member binds acidic and basic fibroblast growth hormone and plays a role in bone development and maintenance. Mutations in this gene lead to craniosynostosis and multiple types of skeletal dysplasia. Three alternatively spliced transcript variants that encode different protein isoforms have been described.
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Molecular Weight
- 85.7 kDa
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NCBI Accession
- NP_000133
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Pathways
- RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Stem Cell Maintenance, Growth Factor Binding
Target
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