Integrin Alpha2b Protein (CD41) (Myc-DYKDDDDK Tag)

Catalog No. ABIN2713707

This Recombinant Integrin Alpha2b protein is produced in HEK-293 Cells.

Quick Overview for Integrin Alpha2b Protein (CD41) (Myc-DYKDDDDK Tag) (ABIN2713707)

Target: Integrin Alpha2b (CD41)

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Application: Antibody Production (AbP), Standard (STD)

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Product Details

Purification tag / Conjugate: This Integrin Alpha2b protein is labelled with Myc-DYKDDDDK Tag.

Characteristics:

• Recombinant human CD41 / ITGA2B protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: Integrin Alpha2b (CD41)

Alternative Name: Cd41,itga2b

Background: This gene encodes a member of the integrin alpha chain family of proteins. The encoded preproprotein is proteolytically processed to generate light and heavy chains that associate through disulfide linkages to form a subunit of the alpha-IIb/beta-3 integrin cell adhesion receptor. This receptor plays a crucial role in the blood coagulation system, by mediating platelet aggregation. Mutations in this gene are associated with platelet-type bleeding disorders, which are characterized by a failure of platelet aggregation, including Glanzmann thrombasthenia.

Molecular Weight: 110 kDa

NCBI Accession: NP_000410

Pathways: Integrin Complex