Integrin Alpha2b Protein (CD41) (AA 639-887, partial) (His-SUMO Tag)
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- Target See all Integrin Alpha2b (CD41) Proteins
- Integrin Alpha2b (CD41)
- Protein Type
- Recombinant
- Protein Characteristics
- AA 639-887, partial
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This Integrin Alpha2b protein is labelled with His-SUMO Tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- CVPQLQLTAS VTGSPLLVGA DNVLELQMDA ANEGEGAYEA ELAVHLPQGA HYMRALSNVE GFERLICNQK KENETRVVLC ELGNPMKKNA QIGIAMLVSV GNLEEAGESV SFQLQIRSKN SQNPNSKIVL LDVPVRAEAQ VELRGNSFPA SLVVAAEEGE REQNSLDSWG PKVEHTYELH NNGPGTVNGL HLSIHLPGQS QPSDLLYILD IQPQGGLQCF PQPPVNPLKV DWGLPIPSPS PIHPAHHKR
- Purification
- SDS-PAGE
- Purity
- > 90 %
- Top Product
- Discover our top product CD41 Protein
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Integrin Alpha2b (CD41) (AA 504-602) protein (GST tag)
CD41 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Integrin Alpha2b (CD41) (AA 891-1039) protein (rho-1D4 tag)Crystallography grade CD41 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Integrin Alpha2b (CD41) (AA 903-1039) protein (rho-1D4 tag)Crystallography grade CD41 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Integrin Alpha2b (CD41) (AA 32-993) protein (His tag)Crystallography grade CD41 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Integrin Alpha2b (CD41) (AA 32-988) protein (His tag)Crystallography grade CD41 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Integrin Alpha2b (CD41) (AA 32-887) protein (rho-1D4 tag)Crystallography grade CD41 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Integrin Alpha2b (CD41) (AA 32-1039) protein (rho-1D4 tag)Crystallography grade CD41 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Integrin Alpha2b (CD41) (AA 32-1033) protein (rho-1D4 tag)Crystallography grade CD41 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Integrin Alpha2b (CD41) (AA 639-887) protein (His tag)CD41 Origin: Human Host: Yeast Recombinant > 90 % SDS
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.1-2 mg/mL
- Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
- Storage
- -80 °C,4 °C,-20 °C
- Storage Comment
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- Target
- Integrin Alpha2b (CD41)
- Alternative Name
- ITA2B (CD41 Products)
- Synonyms
- AI172977 Protein, CD41 Protein, CD41B Protein, GpIIb Protein, alphaIIb Protein, BDPLT16 Protein, BDPLT2 Protein, GP2B Protein, GPIIb Protein, GT Protein, GTA Protein, HPA3 Protein, integrin alpha 2b Protein, integrin subunit alpha 2b Protein, Itga2b Protein, ITGA2B Protein
- Background
- Integrin alpha-IIb/beta-3 is a receptor for fibronectin, fibrinogen, plasminogen, prothrombin, thrombospondin and vitronectin. It recognizes the sequence R-G-D in a wide array of ligands. It recognizes the sequence H-H-L-G-G-G-A-K-Q-A-G-D-V in fibrinogen gamma chain. Following activation integrin alpha-IIb/beta-3 brings about platelet/platelet interaction through binding of soluble fibrinogen. This step leads to rapid platelet aggregation which physically plugs ruptured endothelial cell surface.
- Molecular Weight
- 42.97 kDa
- UniProt
- P08514
- Pathways
- Integrin Complex
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