GLA Protein (Myc-DYKDDDDK Tag)

Catalog No. ABIN2714627

Recombinant GLA protein expressed in HEK-293 Cells.

Quick Overview for GLA Protein (Myc-DYKDDDDK Tag) (ABIN2714627)

Target: GLA (Galactosidase, alpha (GLA))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Application: Antibody Production (AbP), Standard (STD)

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Product Details

Purification tag / Conjugate: This GLA protein is labelled with Myc-DYKDDDDK Tag.

Characteristics:

• Recombinant human Alpha-galactosidase A / GLA protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: GLA (Galactosidase, alpha (GLA))

Alternative Name: alpha-Galactosidase A

Background: This gene encodes a homodimeric glycoprotein that hydrolyses the terminal alpha-galactosyl moieties from glycolipids and glycoproteins. This enzyme predominantly hydrolyzes ceramide trihexoside, and it can catalyze the hydrolysis of melibiose into galactose and glucose. A variety of mutations in this gene affect the synthesis, processing, and stability of this enzyme, which causes Fabry disease, a rare lysosomal storage disorder that results from a failure to catabolize alpha-D-galactosyl glycolipid moieties.

Molecular Weight: 45.3 kDa

NCBI Accession: NP_000160

Pathways: SARS-CoV-2 Protein Interactome