AP2M1 Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)
Quick Overview for AP2M1 Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag) (ABIN2714769)
Target
See all AP2M1 ProteinsProtein Type
Origin
Source
Application
Purity
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Protein Characteristics
- Transcript Variant 2
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Purification tag / Conjugate
- This AP2M1 protein is labelled with Myc-DYKDDDDK Tag.
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Characteristics
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- Recombinant human AP2 complex subunit mu-1 / AP2M1 (transcript variant 2) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- AP2M1 (Adaptor-Related Protein Complex 2, mu 1 Subunit (AP2M1))
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Alternative Name
- Ap2 Complex Subunit mu-1,ap2m1
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Background
- This gene encodes a subunit of the heterotetrameric coat assembly protein complex 2 (AP2), which belongs to the adaptor complexes medium subunits family. The encoded protein is required for the activity of a vacuolar ATPase, which is responsible for proton pumping occurring in the acidification of endosomes and lysosomes. The encoded protein may also play an important role in regulating the intracellular trafficking and function of CTLA-4 protein. Three transcript variants encoding different isoforms have been found for this gene.
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Molecular Weight
- 49.2 kDa
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NCBI Accession
- NP_001020376
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Pathways
- EGFR Signaling Pathway, Neurotrophin Signaling Pathway, EGFR Downregulation, SARS-CoV-2 Protein Interactome
Target
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