ARFGAP1 Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)
Quick Overview for ARFGAP1 Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag) (ABIN2714861)
Target
See all ARFGAP1 ProteinsProtein Type
Origin
Source
Application
Purity
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Protein Characteristics
- Transcript Variant 2
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Purification tag / Conjugate
- This ARFGAP1 protein is labelled with Myc-DYKDDDDK Tag.
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Characteristics
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- Recombinant human ARFGAP1 (transcript variant 2) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- ARFGAP1 (ADP-Ribosylation Factor GTPase Activating Protein 1 (ARFGAP1))
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Alternative Name
- Arfgap1
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Background
- The protein encoded by this gene is a GTPase-activating protein, which associates with the Golgi apparatus and which interacts with ADP-ribosylation factor 1. The encoded protein promotes hydrolysis of ADP-ribosylation factor 1-bound GTP and is required for the dissociation of coat proteins from Golgi-derived membranes and vesicles. Dissociation of the coat proteins is required for the fusion of these vesicles with target compartments. The activity of this protein is stimulated by phosphoinosides and inhibited by phosphatidylcholine. Alternative splicing results in multiple transcript variants.
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Molecular Weight
- 45.5 kDa
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NCBI Accession
- NP_783202
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Pathways
- p53 Signaling, ER-Nucleus Signaling, Unfolded Protein Response
Target
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