beta-2 Microglobulin Protein (Myc-DYKDDDDK Tag)
Quick Overview for beta-2 Microglobulin Protein (Myc-DYKDDDDK Tag) (ABIN2715227)
Target
See all beta-2 Microglobulin (B2M) ProteinsProtein Type
Origin
Source
Application
Purity
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Purification tag / Conjugate
- This beta-2 Microglobulin protein is labelled with Myc-DYKDDDDK Tag.
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Characteristics
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- Recombinant human Beta-2-microglobulin protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- beta-2 Microglobulin (B2M) (beta-2-Microglobulin (B2M))
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Alternative Name
- beta-2-Microglobulin
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Background
- This gene encodes a serum protein found in association with the major histocompatibility complex (MHC) class I heavy chain on the surface of nearly all nucleated cells. The protein has a predominantly beta-pleated sheet structure that can form amyloid fibrils in some pathological conditions. The encoded antimicrobial protein displays antibacterial activity in amniotic fluid. A mutation in this gene has been shown to result in hypercatabolic hypoproteinemia.[provided by RefSeq, Aug 2014].
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Molecular Weight
- 11.7 kDa
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NCBI Accession
- NP_004039
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Pathways
- TCR Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
Target
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