FcRn Protein (Transcript Variant 2)
Quick Overview for FcRn Protein (Transcript Variant 2) (ABIN2720991)
Target
See all FcRn ProteinsProtein Type
Origin
Source
Application
Purity
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Protein Characteristics
- Transcript Variant 2
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Characteristics
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- Recombinant human FCGRT / FCRN (transcript variant 2) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Endotoxin Level
- Endotoxin level is <0.1 ng/μg of protein (<1EU/μg).
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neonatal Fc Receptor (FcRn) (AA 24-297) (Active) protein (His tag)
FcRn Origin: Cynomolgus, Rhesus Monkey Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
neonatal Fc Receptor (FcRn) (AA 22-297) (Active) protein (His tag)FcRn Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
neonatal Fc Receptor (FcRn) (AA 24-297) (Active) protein (His tag)FcRn Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
neonatal Fc Receptor (FcRn) (AA 24-297) protein (His-Avi Tag,Biotin)FcRn Origin: Human Host: HEK-293 Cells Recombinant > 95 % by SEC-HPLC SDS, SPR, SEC-HPLC
neonatal Fc Receptor (FcRn) (AA 24-297) protein (His-Avi Tag)FcRn Origin: Human Host: HEK-293 Cells Recombinant > 95 % by SEC-HPLC SDS, SPR, SEC-HPLC
neonatal Fc Receptor (FcRn) (AA 51-160) protein (GST tag)FcRn Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
neonatal Fc Receptor (FcRn) (AA 22-297) protein (His tag,Strep Tag)FcRn Origin: Mouse Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE.
neonatal Fc Receptor (FcRn) (AA 24-297) (Active) protein (His tag,Strep Tag)FcRn Origin: Cynomolgus, Rhesus Monkey Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
neonatal Fc Receptor (FcRn) (AA 24-297) (Active) protein (His tag,Strep Tag)FcRn Origin: Human Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
neonatal Fc Receptor (FcRn) (AA 24-297) (Active) protein (His tag,Strep Tag,AVI tag,Biotin)FcRn Origin: Human Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Restrictions
- For Research Use only
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Buffer
- Lyophilized from a 0.2 μM filtered solution of PBS, pH 7.4
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Handling Advice
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 μg/mL. Dissolve the lyophilized protein in 1X PBS. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- FcRn (neonatal Fc Receptor (FcRn))
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Alternative Name
- Fcgrt,fcrn
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Background
- This gene encodes a receptor that binds the Fc region of monomeric immunoglobulin G. The encoded protein transfers immunoglobulin G antibodies from mother to fetus across the placenta. This protein also binds immunoglobulin G to protect the antibody from degradation. Alternative splicing results in multiple transcript variants.
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Molecular Weight
- 41.4kD
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NCBI Accession
- NP_004098
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Pathways
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
Target
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