Hexokinase 2 Protein (HK2) (Myc-DYKDDDDK Tag)
Quick Overview for Hexokinase 2 Protein (HK2) (Myc-DYKDDDDK Tag) (ABIN2722680)
Target
See all Hexokinase 2 (HK2) ProteinsProtein Type
Origin
Source
Application
Purity
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Purification tag / Conjugate
- This Hexokinase 2 protein is labelled with Myc-DYKDDDDK Tag.
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Characteristics
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- Recombinant human Hexokinase-2 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Hexokinase 2 (HK2) (AA 1-917) protein (His tag)
custom-made HK2 Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Hexokinase 2 (HK2) (AA 1-917) protein (His tag)custom-made HK2 Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Hexokinase 2 (HK2) (AA 1-917) protein (GST tag)HK2 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Hexokinase 2 (HK2)
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Alternative Name
- Hexokinase-2
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Background
- Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes hexokinase 2, the predominant form found in skeletal muscle. It localizes to the outer membrane of mitochondria. Expression of this gene is insulin-responsive, and studies in rat suggest that it is involved in the increased rate of glycolysis seen in rapidly growing cancer cells.
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Molecular Weight
- 102.2 kDa
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NCBI Accession
- NP_000180
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Pathways
- PI3K-Akt Signaling, Carbohydrate Homeostasis, Warburg Effect
Target
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