HSPB8 Protein (Myc-DYKDDDDK Tag)

Catalog No. ABIN2723117

Recombinant HSPB8 protein expressed in HEK-293 Cells.

Quick Overview for HSPB8 Protein (Myc-DYKDDDDK Tag) (ABIN2723117)

Target: HSPB8 (Heat Shock 22kDa Protein 8 (HSPB8))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Application: Antibody Production (AbP), Standard (STD)

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Product Details

Purification tag / Conjugate: This HSPB8 protein is labelled with Myc-DYKDDDDK Tag.

Characteristics:

• Recombinant human HSPB8 / HSP22 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: HSPB8 (Heat Shock 22kDa Protein 8 (HSPB8))

Alternative Name: Hspb8,hsp22

Background: The protein encoded by this gene belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-terminal part of the molecule. The expression of this gene in induced by estrogen in estrogen receptor-positive breast cancer cells, and this protein also functions as a chaperone in association with Bag3, a stimulator of macroautophagy. Thus, this gene appears to be involved in regulation of cell proliferation, apoptosis, and carcinogenesis, and mutations in this gene have been associated with different neuromuscular diseases, including Charcot-Marie-Tooth disease.

Molecular Weight: 21.4 kDa

NCBI Accession: NP_055180