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IL17RC Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

This Recombinant IL17RC protein is produced in HEK-293 Cells.
Catalog No. ABIN2723367
$1,112.40
Plus shipping costs $50.00, if applicable $20.00 dry ice
20 μg
Shipping to: United States
Delivery in 11 to 12 Business Days

Quick Overview for IL17RC Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag) (ABIN2723367)

Target

See all IL17RC Proteins
IL17RC (Interleukin 17 Receptor C (IL17RC))

Protein Type

Recombinant

Origin

  • 10
  • 2
Human

Source

  • 4
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
HEK-293 Cells

Application

Antibody Production (AbP), Standard (STD)

Purity

> 80 % as determined by SDS-PAGE and Coomassie blue staining
  • Protein Characteristics

    Transcript Variant 1

    Purification tag / Conjugate

    This IL17RC protein is labelled with Myc-DYKDDDDK Tag.

    Characteristics

    • Recombinant human IL17RC (transcript variant 1) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
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  • Application Notes

    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays

    Comment

    The tag is located at the C-terminal.

    Restrictions

    For Research Use only
  • Concentration

    50 μg/mL

    Buffer

    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

    Storage

    -80 °C

    Storage Comment

    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target

    IL17RC (Interleukin 17 Receptor C (IL17RC))

    Alternative Name

    Il17rc

    Background

    This gene encodes a single-pass type I membrane protein that shares similarity with the interleukin-17 receptor (IL-17RA). Unlike IL-17RA, which is predominantly expressed in hemopoietic cells, and binds with high affinity to only IL-17A, this protein is expressed in nonhemopoietic tissues, and binds both IL-17A and IL-17F with similar affinities. The proinflammatory cytokines, IL-17A and IL-17F, have been implicated in the progression of inflammatory and autoimmune diseases. Multiple alternatively spliced transcript variants encoding different isoforms have been detected for this gene, and it has been proposed that soluble, secreted proteins lacking transmembrane and intracellular domains may function as extracellular antagonists to cytokine signaling.

    Molecular Weight

    83.9 kDa

    NCBI Accession

    NP_703191
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