KREMEN2 Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)
Quick Overview for KREMEN2 Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag) (ABIN2724424)
Target
See all KREMEN2 ProteinsProtein Type
Origin
Source
Application
Purity
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Protein Characteristics
- Transcript Variant 2
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Purification tag / Conjugate
- This KREMEN2 protein is labelled with Myc-DYKDDDDK Tag.
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Characteristics
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- Recombinant human Kremen protein 2 (transcript variant 2) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Kringle Containing Transmembrane Protein 2 (KREMEN2) (AA 26-364) (Active) protein (His tag)
KREMEN2 Origin: Cynomolgus Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Kringle Containing Transmembrane Protein 2 (KREMEN2) (AA 1-420) protein (GST tag)KREMEN2 Origin: Human Host: Wheat germ Recombinant AP, AA, ELISA, WB
Kringle Containing Transmembrane Protein 2 (KREMEN2) (AA 26-364) protein (His tag)KREMEN2 Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining. AM, ADA, IA, ScA
Kringle Containing Transmembrane Protein 2 (KREMEN2) (AA 25-363) (Active) protein (His tag)KREMEN2 Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE Active
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- KREMEN2 (Kringle Containing Transmembrane Protein 2 (KREMEN2))
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Alternative Name
- Kremen Protein 2
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Background
- This gene encodes a high-affinity dickkopf homolog 1 (DKK1) transmembrane receptor. A similar protein in mouse functions interacts with with DKK1 to block wingless (WNT)/beta-catenin signaling. The encoded protein forms a ternary membrane complex with DKK1 and the WNT receptor lipoprotein receptor-related protein 6 (LRP6), and induces rapid endocytosis and removal of LRP6 from the plasma membrane. It contains extracellular kringle, WSC, and CUB domains. Alternatively spliced transcript variants encoding distinct isoforms have been observed for this gene.
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Molecular Weight
- 42.3 kDa
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NCBI Accession
- NP_078783
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Pathways
- WNT Signaling
Target
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