KREMEN2 Protein (AA 26-364) (His tag)
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- Target See all KREMEN2 Proteins
- KREMEN2 (Kringle Containing Transmembrane Protein 2 (KREMEN2))
- Protein Type
- Recombinant
- Biological Activity
- Active
- Protein Characteristics
- AA 26-364
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This KREMEN2 protein is labelled with His tag.
- Purpose
- Human Kremen-2 protein, His Tag
- Purity
- >95 % as determined by reduced SDS-PAGE.
- Endotoxin Level
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product KREMEN2 Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- PBS, 0.2M Arginine, pH 7.4
- Storage
- -20 °C
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- Target
- KREMEN2 (Kringle Containing Transmembrane Protein 2 (KREMEN2))
- Alternative Name
- KREMEN2 (KREMEN2 Products)
- Synonyms
- krm2 Protein, KREMEN2 Protein, MGC147633 Protein, KRM2 Protein, 2900054E04Rik Protein, Krm2 Protein, kringle containing transmembrane protein 2 S homeolog Protein, kringle containing transmembrane protein 2 Protein, kremen2.S Protein, KREMEN2 Protein, kremen2 Protein, Kremen2 Protein
- Background
- Kremen2 (Krm2) plays an important role in embryonic development, bone formation, and tumorigenesis as a crucial regulator of classical Wnt/β-catenin signaling pathway. Krm1 and its paralog Krm2 share the ability to bind Dkk1 and inhibit Wnt signaling, both processes previously shown to rely on the extracellular domain. Previous studies have shown that Krm2 may be involved in embryonic development, bone formation, neural ridge formation and tumorigenesis and could be a biomarker of grading and a potential therapeutic target in gastric cancer.
- Molecular Weight
- 38.0 kDa
- Pathways
- WNT Signaling
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