LY96 Protein (Myc-DYKDDDDK Tag)

Catalog No. ABIN2725664

Recombinant LY96 protein expressed in HEK-293 Cells and has been mentioned in 1 publication.

Quick Overview for LY96 Protein (Myc-DYKDDDDK Tag) (ABIN2725664)

Target: LY96 (Lymphocyte Antigen 96 (LY96))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Application: Antibody Production (AbP), Standard (STD)

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Product Details

Purification tag / Conjugate: This LY96 protein is labelled with Myc-DYKDDDDK Tag.

Characteristics:

• Recombinant human MD-2 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

References

Dulay, Buhimschi, Zhao, Oliver, Abdel-Razeq, Shook, Bahtiyar, Buhimschi: "Amniotic Fluid Soluble Myeloid Differentiation-2 (sMD-2) as Regulator of Intra-amniotic Inflammation in Infection-induced Preterm Birth." in: American journal of reproductive immunology (New York, N.Y. : 1989), Vol. 73, Issue 6, pp. 507-21, (2015) (PubMed).

Target Details

Target: LY96 (Lymphocyte Antigen 96 (LY96))

Alternative Name: Md-2

Background: This gene encodes a protein which associates with toll-like receptor 4 on the cell surface and confers responsiveness to lipopolysaccyaride (LPS), thus providing a link between the receptor and LPS signaling. Studies of the mouse ortholog suggest that this gene may be involved in endotoxin neutralization. Alternative splicing results in multiple transcript variants encoding different isoforms.

Molecular Weight: 18.4 kDa

NCBI Accession: NP_056179

Pathways: TLR Signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades