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LY96 Protein (Myc-DYKDDDDK Tag)

LY96 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2725664
  • Target See all LY96 Proteins
    LY96 (Lymphocyte Antigen 96 (LY96))
    Protein Type
    Recombinant
    Origin
    • 5
    • 4
    • 1
    • 1
    • 1
    Human
    Source
    • 5
    • 2
    • 2
    • 2
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This LY96 protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human MD-2 protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product LY96 Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Dulay, Buhimschi, Zhao, Oliver, Abdel-Razeq, Shook, Bahtiyar, Buhimschi: "Amniotic Fluid Soluble Myeloid Differentiation-2 (sMD-2) as Regulator of Intra-amniotic Inflammation in Infection-induced Preterm Birth." in: American journal of reproductive immunology (New York, N.Y. : 1989), Vol. 73, Issue 6, pp. 507-21, (2015) (PubMed).

  • Target
    LY96 (Lymphocyte Antigen 96 (LY96))
    Alternative Name
    Md-2 (LY96 Products)
    Synonyms
    MD2 Protein, ESOP-1 Protein, MD-2 Protein, ly-96 Protein, Ly-96 Protein, Md2 Protein, lymphocyte antigen 96 Protein, LY96 Protein, Ly96 Protein
    Background
    This gene encodes a protein which associates with toll-like receptor 4 on the cell surface and confers responsiveness to lipopolysaccyaride (LPS), thus providing a link between the receptor and LPS signaling. Studies of the mouse ortholog suggest that this gene may be involved in endotoxin neutralization. Alternative splicing results in multiple transcript variants encoding different isoforms.
    Molecular Weight
    18.4 kDa
    NCBI Accession
    NP_056179
    Pathways
    TLR Signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
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