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LY96 Protein (Fc Tag)

LY96 Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE
Catalog No. ABIN7320047
  • Target See all LY96 Proteins
    LY96 (Lymphocyte Antigen 96 (LY96))
    Protein Type
    Recombinant
    Origin
    • 6
    • 3
    • 1
    • 1
    • 1
    Mouse
    Source
    • 5
    • 2
    • 2
    • 2
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This LY96 protein is labelled with Fc Tag.
    Purpose
    Recombinant Mouse LY-96/ESOP-1 Protein (Fc Tag)
    Sequence
    Met1-Asn160
    Characteristics
    A DNA sequence encoding the mouse LY96 (Q9JHF9) (Met1-Asn160) was expressed with the Fc region of human IgG1 at the C-terminus.
    Purity
    > 95 % as determined by SDS-PAGE
    Endotoxin Level
    < 1.0 EU per μg of the protein as determined by the LAL method.
    Top Product
    Discover our top product LY96 Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Please refer to the printed manual for detailed information.
    Buffer
    Lyophilized from sterile PBS, pH 7.4
    Storage
    4 °C,-20 °C,-80 °C
    Storage Comment
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target
    LY96 (Lymphocyte Antigen 96 (LY96))
    Alternative Name
    LY-96/ESOP-1 (LY96 Products)
    Synonyms
    MD2 Protein, ESOP-1 Protein, MD-2 Protein, ly-96 Protein, Ly-96 Protein, Md2 Protein, lymphocyte antigen 96 Protein, LY96 Protein, Ly96 Protein
    Background

    Background: LY-96, also known as ESOP-1, is a protein which associates with toll-like receptor 4 on the cell surface and confers responsiveness to lipopolysaccyaride (LPS). LY-96 also cooperates with TLR2 in the response to cell wall components from Gram-positive and Gram-negative bacteria. It enhances TLR4-dependent activation of NF-kappa-B. ESOP-1 has 160 amino acids, the sequence of which shows 64 % identity with human ESOP-1/MD-2. ESOP-1 mRNA is highly expressed in the mouse embryos at 7.5 days after coitus.

    Synonym: ESOP-1,MD-2,MD2

    Molecular Weight
    43.4 kDa
    UniProt
    Q9JHF9
    Pathways
    TLR Signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
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