LY96 Protein (Fc Tag)

Catalog No. ABIN7320047

This Recombinant LY96 protein is produced in HEK-293 Cells.

Quick Overview for LY96 Protein (Fc Tag) (ABIN7320047)

Target: LY96 (Lymphocyte Antigen 96 (LY96))

Protein Type: Recombinant

Origin: Mouse

Source: HEK-293 Cells

Purity: > 95 % as determined by SDS-PAGE

Product Details

Purification tag / Conjugate: This LY96 protein is labelled with Fc Tag.

Purpose: Recombinant Mouse LY-96/ESOP-1 Protein (Fc Tag)

Sequence: Met1-Asn160

Characteristics: A DNA sequence encoding the mouse LY96 (Q9JHF9) (Met1-Asn160) was expressed with the Fc region of human IgG1 at the C-terminus.

Endotoxin Level: < 1.0 EU per μg of the protein as determined by the LAL method.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from sterile PBS, pH 7.4

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Target Details

Target: LY96 (Lymphocyte Antigen 96 (LY96))

Alternative Name: LY-96/ESOP-1

Background:

Background: LY-96, also known as ESOP-1, is a protein which associates with toll-like receptor 4 on the cell surface and confers responsiveness to lipopolysaccyaride (LPS). LY-96 also cooperates with TLR2 in the response to cell wall components from Gram-positive and Gram-negative bacteria. It enhances TLR4-dependent activation of NF-kappa-B. ESOP-1 has 160 amino acids, the sequence of which shows 64 % identity with human ESOP-1/MD-2. ESOP-1 mRNA is highly expressed in the mouse embryos at 7.5 days after coitus.

Synonym: ESOP-1,MD-2,MD2

Molecular Weight: 43.4 kDa

UniProt: Q9JHF9

Pathways: TLR Signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades