MYD88 Protein (Myc-DYKDDDDK Tag)
Quick Overview for MYD88 Protein (Myc-DYKDDDDK Tag) (ABIN2726637)
Target
See all MYD88 ProteinsProtein Type
Origin
Source
Application
Purity
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Purification tag / Conjugate
- This MYD88 protein is labelled with Myc-DYKDDDDK Tag.
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Characteristics
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- Recombinant human MYD88 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Myeloid Differentiation Primary Response Gene (88) (MYD88) (AA 1-296) protein (His tag)
custom-made MYD88 Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Myeloid Differentiation Primary Response Gene (88) (MYD88) (AA 1-296) protein (His tag)custom-made MYD88 Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Myeloid Differentiation Primary Response Gene (88) (MYD88) (AA 1-296) protein (GST tag)MYD88 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Myeloid Differentiation Primary Response Gene (88) (MYD88) proteinMYD88 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % pure SDS
Myeloid Differentiation Primary Response Gene (88) (MYD88) (AA 31-130) protein (GST tag)MYD88 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- MYD88 (Myeloid Differentiation Primary Response Gene (88) (MYD88))
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Alternative Name
- Myd88
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Background
- This gene encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. This protein functions as an essential signal transducer in the interleukin-1 and Toll-like receptor signaling pathways. These pathways regulate that activation of numerous proinflammatory genes. The encoded protein consists of an N-terminal death domain and a C-terminal Toll-interleukin1 receptor domain. Patients with defects in this gene have an increased susceptibility to pyogenic bacterial infections. Alternate splicing results in multiple transcript variants.
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Molecular Weight
- 33.1 kDa
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NCBI Accession
- NP_002459
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Pathways
- NF-kappaB Signaling, TLR Signaling, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades
Target
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