NFASC Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)
Quick Overview for NFASC Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag) (ABIN2727124)
Target
See all NFASC ProteinsProtein Type
Origin
Source
Application
Purity
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Protein Characteristics
- Transcript Variant 2
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Purification tag / Conjugate
- This NFASC protein is labelled with Myc-DYKDDDDK Tag.
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Characteristics
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- Recombinant human Neurofascin (transcript variant 2) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Neurofascin (NFASC) protein (Fc Tag)
NFASC Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
Neurofascin (NFASC) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)NFASC Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Neurofascin (NFASC) (AA 1239-1347) protein (His tag)NFASC Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % SDS
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- NFASC (Neurofascin (NFASC))
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Alternative Name
- Neurofascin
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Background
- This gene encodes an L1 family immunoglobulin cell adhesion molecule with multiple IGcam and fibronectin domains. The protein functions in neurite outgrowth, neurite fasciculation, and organization of the axon initial segment (AIS) and nodes of Ranvier on axons during early development. Both the AIS and nodes of Ranvier contain high densities of voltage-gated Na+ (Nav) channels which are clustered by interactions with cytoskeletal and scaffolding proteins including this protein, gliomedin, ankyrin 3 (ankyrin-G), and betaIV spectrin. This protein links the AIS extracellular matrix to the intracellular cytoskeleton. This gene undergoes extensive alternative splicing, and the full-length nature of some variants has not been determined.[provided by RefSeq, May 2009].
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Molecular Weight
- 131.1 kDa
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NCBI Accession
- NP_001153803
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Pathways
- Cell-Cell Junction Organization
Target
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