KAT2B Protein (Myc-DYKDDDDK Tag)

Catalog No. ABIN2728343

Recombinant KAT2B protein expressed in HEK-293 Cells.

Quick Overview for KAT2B Protein (Myc-DYKDDDDK Tag) (ABIN2728343)

Target: KAT2B (K(lysine) Acetyltransferase 2B (KAT2B))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Application: Antibody Production (AbP), Standard (STD)

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Product Details

Purification tag / Conjugate: This KAT2B protein is labelled with Myc-DYKDDDDK Tag.

Characteristics:

• Recombinant human PCAF / KAT2B protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: KAT2B (K(lysine) Acetyltransferase 2B (KAT2B))

Alternative Name: Pcaf,kat2b

Background: CBP and p300 are large nuclear proteins that bind to many sequence-specific factors involved in cell growth and/or differentiation, including c-jun and the adenoviral oncoprotein E1A. The protein encoded by this gene associates with p300/CBP. It has in vitro and in vivo binding activity with CBP and p300, and competes with E1A for binding sites in p300/CBP. It has histone acetyl transferase activity with core histones and nucleosome core particles, indicating that this protein plays a direct role in transcriptional regulation.

Molecular Weight: 92.8 kDa

NCBI Accession: NP_003875

Pathways: p53 Signaling, Regulation of Carbohydrate Metabolic Process