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KAT2B Protein (DYKDDDDK Tag)

KAT2B Origin: Human Host: Insect cells (Sf9) Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2728344
  • Target See all KAT2B Proteins
    KAT2B (K(lysine) Acetyltransferase 2B (KAT2B))
    Protein Type
    Recombinant
    Origin
    • 10
    • 1
    Human
    Source
    • 6
    • 2
    • 2
    • 1
    Insect cells (Sf9)
    Purification tag / Conjugate
    This KAT2B protein is labelled with DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human PCAF / KAT2B (full length, C-term DDK tag) protein expressed in Sf9 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product KAT2B Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    50 mM Tris-HCl pH 8.0, 150 mM NaCl, 20 % glycerol. Store at -80C. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    KAT2B (K(lysine) Acetyltransferase 2B (KAT2B))
    Alternative Name
    Pcaf,kat2b (KAT2B Products)
    Synonyms
    PCAF Protein, pcaf Protein, si:ch211-1j13.2 Protein, zgc:161980 Protein, gb:dq017634 Protein, im:7156024 Protein, CAF Protein, P Protein, P/CAF Protein, A930006P13Rik Protein, AI461839 Protein, AW536563 Protein, Pcaf Protein, p/CAF Protein, lysine acetyltransferase 2B Protein, K(lysine) acetyltransferase 2B Protein, K(lysine) acetyltransferase 2A Protein, KAT2B Protein, kat2b Protein, kat2a Protein, Kat2b Protein
    Background
    CBP and p300 are large nuclear proteins that bind to many sequence-specific factors involved in cell growth and/or differentiation, including c-jun and the adenoviral oncoprotein E1A. The protein encoded by this gene associates with p300/CBP. It has in vitro and in vivo binding activity with CBP and p300, and competes with E1A for binding sites in p300/CBP. It has histone acetyl transferase activity with core histones and nucleosome core particles, indicating that this protein plays a direct role in transcriptional regulation.
    Molecular Weight
    93 kDa
    NCBI Accession
    NP_003875
    Pathways
    p53 Signaling, Regulation of Carbohydrate Metabolic Process
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