KAT2B Protein (DYKDDDDK Tag)
-
- Target See all KAT2B Proteins
- KAT2B (K(lysine) Acetyltransferase 2B (KAT2B))
- Protein Type
- Recombinant
-
Origin
- Human
-
Source
- Insect cells (Sf9)
- Purification tag / Conjugate
- This KAT2B protein is labelled with DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
-
- Recombinant human PCAF / KAT2B (full length, C-term DDK tag) protein expressed in Sf9 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product KAT2B Protein
-
-
- Application Notes
-
Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
-
The tag is located at the C-terminal.
- Restrictions
- For Research Use only
-
- Concentration
- 50 μg/mL
- Buffer
- 50 mM Tris-HCl pH 8.0, 150 mM NaCl, 20 % glycerol. Store at -80C. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
-
- Target
- KAT2B (K(lysine) Acetyltransferase 2B (KAT2B))
- Alternative Name
- Pcaf,kat2b (KAT2B Products)
- Synonyms
- PCAF Protein, pcaf Protein, si:ch211-1j13.2 Protein, zgc:161980 Protein, gb:dq017634 Protein, im:7156024 Protein, CAF Protein, P Protein, P/CAF Protein, A930006P13Rik Protein, AI461839 Protein, AW536563 Protein, Pcaf Protein, p/CAF Protein, lysine acetyltransferase 2B Protein, K(lysine) acetyltransferase 2B Protein, K(lysine) acetyltransferase 2A Protein, KAT2B Protein, kat2b Protein, kat2a Protein, Kat2b Protein
- Background
- CBP and p300 are large nuclear proteins that bind to many sequence-specific factors involved in cell growth and/or differentiation, including c-jun and the adenoviral oncoprotein E1A. The protein encoded by this gene associates with p300/CBP. It has in vitro and in vivo binding activity with CBP and p300, and competes with E1A for binding sites in p300/CBP. It has histone acetyl transferase activity with core histones and nucleosome core particles, indicating that this protein plays a direct role in transcriptional regulation.
- Molecular Weight
- 93 kDa
- NCBI Accession
- NP_003875
- Pathways
- p53 Signaling, Regulation of Carbohydrate Metabolic Process
-