PDZK1 Protein (Myc-DYKDDDDK Tag)
Quick Overview for PDZK1 Protein (Myc-DYKDDDDK Tag) (ABIN2728618)
Target
See all PDZK1 ProteinsProtein Type
Origin
Source
Application
Purity
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Purification tag / Conjugate
- This PDZK1 protein is labelled with Myc-DYKDDDDK Tag.
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Characteristics
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- Recombinant human PDZD1 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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PDZ Domain Containing 1 (PDZK1) (AA 1-519) protein (GST tag)
PDZK1 Origin: Human Host: Wheat germ Recombinant AP, AA, ELISA, WB
PDZ Domain Containing 1 (PDZK1) (AA 1-519) protein (His tag)PDZK1 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % SDS
PDZ Domain Containing 1 (PDZK1) (AA 1-519), (full length) protein (His tag)PDZK1 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. SDS
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- PDZK1 (PDZ Domain Containing 1 (PDZK1))
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Alternative Name
- Pdzd1
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Background
- This gene encodes a PDZ domain-containing scaffolding protein. PDZ domain-containing molecules bind to and mediate the subcellular localization of target proteins. The encoded protein mediates the localization of cell surface proteins and plays a critical role in cholesterol metabolism by regulating the HDL receptor, scavenger receptor class B type 1. Single nucleotide polymorphisms in this gene may be associated with metabolic syndrome, and overexpression of this gene may play a role in drug resistance of multiple myeloma. Pseudogenes of this gene are located on the long arm of chromosome 1. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
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Molecular Weight
- 56.9 kDa
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NCBI Accession
- NP_002605
Target
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