PDZK1 Protein (AA 1-519, full length) (His tag)
PDZK1
Origin: Human
Host: Escherichia coli (E. coli)
Recombinant
> 90 %
SDS
1 image
-
- Target See all PDZK1 Proteins
- PDZK1 (PDZ Domain Containing 1 (PDZK1))
- Protein Type
- Recombinant
- Protein Characteristics
- full length, AA 1-519
-
Origin
- Human
-
Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This PDZK1 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- MTSTFNPREC KLSKQEGQNY GFFLRIEKDT EGHLVRVVEK CSPAEKAGLQ DGDRVLRING VFVDKEEHMQ VVDLVRKSGN SVTLLVLDGD SYEKAVKTRV DLKELGQSQK EQGLSDNILS PVMNGGVQTW TQPRLCYLVK EGGSYGFSLK TVQGKKGVYM TDITPQGVAM RAGVLADDHL IEVNGENVED ASHEEVVEKV KKSGSRVMFL LVDKETDKRH VEQKIQFKRE TASLKLLPHQ PRIVEMKKGS NGYGFYLRAG SEQKGQIIKD IDSGSPAEEA GLKNNDLVVA VNGESVETLD HDSVVEMIRK GGDQTSLLVV DKETDNMYRL AHFSPFLYYQ SQELPNGSVK EAPAPTPTSL EVSSPPDTTE EVDHKPKLCR LAKGENGYGF HLNAIRGLPG SFIKEVQKGG PADLAGLEDE DVIIEVNGVN VLDEPYEKVV DRIQSSGKNV TLLVCGKKAY DYFQAKKIPI VSSLADPLDT PPDSKEGIVV ESNHDSHMAK ERAHSTASHS SSNSEDTEM
- Purification
- SDS-PAGE
- Purity
- > 90 %
- Top Product
- Discover our top product PDZK1 Protein
-
PDZ Domain Containing 1 (PDZK1) (AA 1-519) protein (GST tag)
PDZK1 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
PDZ Domain Containing 1 (PDZK1) protein (Myc-DYKDDDDK Tag)PDZK1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
-
- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 0.1-2 mg/mL
- Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
- Storage
- -80 °C,4 °C,-20 °C
- Storage Comment
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
-
- Target
- PDZK1 (PDZ Domain Containing 1 (PDZK1))
- Alternative Name
- NHRF3 (PDZK1 Products)
- Synonyms
- xpdzk1 Protein, PDZK1 Protein, CAP70 Protein, CLAMP Protein, NHERF-3 Protein, NHERF3 Protein, PDZD1 Protein, 1700023D20Rik Protein, 2610507N21Rik Protein, 4921513F16Rik Protein, AI267131 Protein, AI314638 Protein, AL022680 Protein, D3Ertd537e Protein, Pdzd1 Protein, mPDZK1 Protein, Clamp Protein, PDZ domain containing 1 Protein, PDZ domain containing 1 L homeolog Protein, PDZK1 Protein, pdzk1.L Protein, pdzk1 Protein, Pdzk1 Protein
- Background
- A scaffold protein that connects plasma mbrane proteins and regulatory components, regulating their surface expression in epithelial cells apical domains. May be involved in the coordination of a diverse range of regulatory processes for ion transport and second messenger cascades. In complex with SLC9A3R1, may cluster proteins that are functionally dependent in a mutual fashion and modulate the trafficking and the activity of the associated mbrane proteins. May play a role in the cellular mechanisms associated with multidrug resistance through its interaction with ABCC2 and PDZK1IP1. May potentiate the CFTR chloride channel activity. Required for normal cell-surface expression of SCARB1. Plays a role in maintaining normal plasma cholesterol levels via its effects on SCARB1. Plays a role in the normal localization and function of the chloride-anion exchanger SLC26A6 to the plasma mbrane in the brush border of the proximal tubule of the kidney. May be involved in the regulation of proximal tubular Na+-dependent inorganic phosphate cotransport therefore playing an important role in tubule function .
- Molecular Weight
- 61.2 kDa
- UniProt
- Q5T2W1
-
You are here:
