Quick Overview for PFKFB1 Protein (Myc-DYKDDDDK Tag) (ABIN2728745)
Target
See all PFKFB1 ProteinsProtein Type
Origin
Source
Application
Purity
-
-
Purification tag / Conjugate
- This PFKFB1 protein is labelled with Myc-DYKDDDDK Tag.
-
Characteristics
-
- Recombinant human PFKFB1 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
-
-
Want other Options for this Protein ?
!Discover Our Predefined Custom Proteins and Custom Protein Services!Your project requires further customization? Contact us and discover our custom protein solutions
-
6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 1 (PFKFB1) (AA 1-471) protein (GST tag)
PFKFB1 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 1 (PFKFB1) protein (His tag)PFKFB1 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
-
-
Application Notes
-
Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
-
The tag is located at the C-terminal.
-
Restrictions
- For Research Use only
-
-
-
Concentration
- 50 μg/mL
-
Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
-
Storage
- -80 °C
-
Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
-
-
- PFKFB1 (6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 1 (PFKFB1))
-
Alternative Name
- Pfkfb1
-
Background
- This gene encodes a member of the family of bifunctional 6-phosphofructo-2-kinase:fructose-2,6-biphosphatase enzymes. The enzyme forms a homodimer that catalyzes both the synthesis and degradation of fructose-2,6-biphosphate using independent catalytic domains. Fructose-2,6-biphosphate is an activator of the glycolysis pathway and an inhibitor of the gluconeogenesis pathway. Consequently, regulating fructose-2,6-biphosphate levels through the activity of this enzyme is thought to regulate glucose homeostasis. Multiple alternatively spliced transcript variants have been found for this gene.
-
Molecular Weight
- 54.5 kDa
-
NCBI Accession
- NP_002616
-
Pathways
- Regulation of Carbohydrate Metabolic Process
Target
-
