PFKFB1 Protein (His tag)
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- Target See all PFKFB1 Proteins
- PFKFB1 (6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 1 (PFKFB1))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Human Cells
- Purification tag / Conjugate
- This PFKFB1 protein is labelled with His tag.
- Purpose
- Recombinant Human PFKFB1 Protein (His Tag)
- Sequence
- Ser2-Tyr471
- Characteristics
- Recombinant Human 6-Phosphofructo-2-kinase/Fructose-2,6-bisphosphatase 1 is produced by our Mammalian expression system and the target gene encoding Ser2-Tyr471 is expressed with a 6His tag at the C-terminus.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product PFKFB1 Protein
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6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 1 (PFKFB1) (AA 1-100) protein (GST tag)
PFKFB1 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 1 (PFKFB1) (AA 1-471) protein (GST tag)PFKFB1 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 1 (PFKFB1) (AA 2-471) protein (His tag)Crystallography grade PFKFB1 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS, Crys
6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 1 (PFKFB1) (AA 2-471) protein (His tag)Crystallography grade PFKFB1 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS, Crys
6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 1 (PFKFB1) protein (His tag)PFKFB1 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 1 (PFKFB1) protein (Myc-DYKDDDDK Tag)PFKFB1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Restrictions
- For Research Use only
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- Format
- Frozen, Liquid
- Buffer
- Supplied as a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.
- Storage
- -20 °C
- Storage Comment
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- Target
- PFKFB1 (6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 1 (PFKFB1))
- Alternative Name
- PFKFB1 (PFKFB1 Products)
- Synonyms
- zgc:55328 Protein, wu:fi11h10 Protein, PFKFB1 Protein, F6PK Protein, HL2K Protein, PFRX Protein, Pfkfb01 Protein, 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 Protein, 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 S homeolog Protein, 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 Protein, pfkfb1 Protein, PFKFB1 Protein, pfkfb1.S Protein, LOC100475853 Protein, Pfkfb1 Protein
- Background
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Background: 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 is an enzyme that in humans is encoded by the PFKFB1 gene. The enzyme forms a homodimer that catalyzes both the synthesis and degradation of fructose-2,6-biphosphate using independent catalytic domains. It belongs to the phosphoglycerate mutase family. Fructose-2,6-biphosphate is an activator of the glycolysis pathway and an inhibitor of the gluconeogenesis pathway. Consequently, regulating fructose-2,6-biphosphate levels through the activity of this enzyme is thought to regulate glucose homeostasis.
Synonym: 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1, 6PF-2-K/Fru-2,6-P2ase liver isozyme, Fructose-2,6-bisphosphatase, PFKFB1, F6PK, PFRX
- Molecular Weight
- 55.6 kDa
- UniProt
- P16118
- Pathways
- Regulation of Carbohydrate Metabolic Process
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