POLD2 Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)
Quick Overview for POLD2 Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag) (ABIN2729300)
Target
See all POLD2 ProteinsProtein Type
Origin
Source
Application
Purity
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Protein Characteristics
- Transcript Variant 2
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Purification tag / Conjugate
- This POLD2 protein is labelled with Myc-DYKDDDDK Tag.
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Characteristics
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- Recombinant human POLD2 (transcript variant 2) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- POLD2 (Polymerase (DNA Directed), delta 2, Accessory Subunit (POLD2))
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Alternative Name
- Pold2
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Background
- This gene encodes the 50- kDa catalytic subunit of DNA polymerase delta. DNA polymerase delta possesses both polymerase and 3' to 5' exonuclease activity and plays a critical role in DNA replication and repair. The encoded protein is required for the stimulation of DNA polymerase delta activity by the processivity cofactor proliferating cell nuclear antigen (PCNA). Expression of this gene may be a marker for ovarian carcinomas. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 5.
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Molecular Weight
- 51.1 kDa
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NCBI Accession
- NP_006221
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Pathways
- Telomere Maintenance, DNA Damage Repair, DNA Replication, Synthesis of DNA
Target
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