PRR5 Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)
This Recombinant PRR5 protein is produced in HEK-293 Cells.
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Catalog No. ABIN2729850
$1,112.40
Plus shipping costs $50.00, if applicable $20.00 dry ice
20 μg
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United States
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Quick Overview for PRR5 Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag) (ABIN2729850)
Target
See all PRR5 Proteins
PRR5
(Proline Rich 5 (Renal) (PRR5))
Protein Type
Recombinant
Origin
Human
Source
HEK-293 Cells
Application
Antibody Production (AbP), Standard (STD)
Purity
> 80 % as determined by SDS-PAGE and Coomassie blue staining
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Protein Characteristics
- Transcript Variant 2
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Purification tag / Conjugate
- This PRR5 protein is labelled with Myc-DYKDDDDK Tag.
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Characteristics
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- Recombinant human PRR5 (transcript variant 2) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- PRR5 (Proline Rich 5 (Renal) (PRR5))
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Alternative Name
- Prr5
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Background
- This gene encodes a protein with a proline-rich domain. This gene is located in a region of chromosome 22 reported to contain a tumor suppressor gene that may be involved in breast and colorectal tumorigenesis. The protein is a component of the mammalian target of rapamycin complex 2 (mTORC2), and it regulates platelet-derived growth factor (PDGF) receptor beta expression and PDGF signaling to Akt and S6K1. Alternative splicing and the use of alternative promoters results in transcripts encoding different isoforms. Read-through transcripts from this gene into the downstream Rho GTPase activating protein 8 (ARHGAP8) gene also exist, which led to the original description of PRR5 and ARHGAP8 being a single gene.
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Molecular Weight
- 41.4 kDa
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NCBI Accession
- NP_056181
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Pathways
- PI3K-Akt Signaling
Target
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