RAC1 Protein (Myc-DYKDDDDK Tag)

Catalog No. ABIN2730391

Product Details

Target: RAC1

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This RAC1 protein is labelled with Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human RAC1 (transcript variant Rac1) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: RAC1

Abstract: RAC1 Products

Synonyms: Rac-1 Protein, TC-25 Protein, p21-Rac1 Protein, AL023026 Protein, D5Ertd559e Protein, RAC2 Protein, CRAC1A Protein, rac1 Protein, wu:fd16e02 Protein, zgc:55823 Protein, zgc:55917 Protein, zgc:86934 Protein, 2248 Protein, CG2248 Protein, D-Rac Protein, D-Rac 1 Protein, D-Rac1 Protein, DRac Protein, DRac1 Protein, DRacA Protein, Dm Rac1 Protein, DmRAC Protein, DmRAC1 Protein, Dmel\CG2248 Protein, Dmrac1 Protein, Drac Protein, Drac1 Protein, Drac1a Protein, DracA Protein, GTPase Rac1 Protein, P40792 Protein, RAC1 Protein, Rac Protein, Rac GTPase Protein, Rac3 Protein, RacA Protein, dRac Protein, dRac1 Protein, drac1 Protein, rac Protein, Xrac Protein, mig5 Protein, p21-rac1 Protein, tc-25 Protein, Rac family small GTPase 1 Protein, RAS-related C3 botulinum substrate 1 Protein, ras-related C3 botulinum toxin substrate 1 Protein, ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) Protein, Rac family small GTPase 1a Protein, CG2248 gene product from transcript CG2248-RB Protein, Rac family small GTPase 1 L homeolog Protein, ras homolog family member G Protein, RAC1 Protein, Rac1 Protein, rac1a Protein, rac1.L Protein, RHOG Protein

Background: Isoform B has an accelerated GEF-independent GDP/GTP exchange and an impaired GTP hydrolysis, which is restored partially by GTPase-activating proteins. It is able to bind to the GTPase-binding domain of PAK but not full-length PAK in a GTP-dependent manner, suggesting that the insertion does not completely abolish effector interaction. [UniProtKB/Swiss-Prot Function]

Molecular Weight: 21.3 kDa

NCBI Accession: NP_008839

Pathways: WNT Signaling, Regulation of Actin Filament Polymerization, Cell-Cell Junction Organization, Thromboxane A2 Receptor Signaling, VEGF Signaling