RAD23B Protein (Myc-DYKDDDDK Tag)
Quick Overview for RAD23B Protein (Myc-DYKDDDDK Tag) (ABIN2730408)
Target
See all RAD23B ProteinsProtein Type
Origin
Source
Application
Purity
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Purification tag / Conjugate
- This RAD23B protein is labelled with Myc-DYKDDDDK Tag.
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Characteristics
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- Recombinant human RAD23B protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- RAD23B (RAD23 Homolog B (RAD23B))
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Alternative Name
- Rad23b
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Background
- The protein encoded by this gene is one of two human homologs of Saccharomyces cerevisiae Rad23, a protein involved in the nucleotide excision repair (NER). This protein was found to be a component of the protein complex that specifically complements the NER defect of xeroderma pigmentosum group C (XP-c) cell extracts in vitro. This protein was also shown to interact with, and elevate the nucleotide excision activity of 3-methyladenine-DNA glycosylase (MPG), which suggested a role in DNA damage recognition in base excision repair. This protein contains an N-terminal ubiquitin-like domain, which was reported to interact with 26S proteasome, and thus this protein may be involved in the ubiquitin mediated proteolytic pathway in cells. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
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Molecular Weight
- 43 kDa
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NCBI Accession
- NP_002865
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Pathways
- DNA Damage Repair
Target
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