RAPSN Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

Catalog No. ABIN2730492

This Recombinant RAPSN protein is produced in HEK-293 Cells.

Quick Overview for RAPSN Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag) (ABIN2730492)

Target: RAPSN (Receptor-Associated Protein of The Synapse (RAPSN))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Application: Antibody Production (AbP), Standard (STD)

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Product Details

Protein Characteristics: Transcript Variant 1

Purification tag / Conjugate: This RAPSN protein is labelled with Myc-DYKDDDDK Tag.

Characteristics:

• Recombinant human RAPSN / RNF205 (transcript variant 1) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: RAPSN (Receptor-Associated Protein of The Synapse (RAPSN))

Alternative Name: Rapsn,rnf205

Background: This gene encodes a member of a family of proteins that are receptor associated proteins of the synapse. The encoded protein contains a conserved cAMP-dependent protein kinase phosphorylation site, and plays a critical role in clustering and anchoring nicotinic acetylcholine receptors at synaptic sites by linking the receptors to the underlying postsynaptic cytoskeleton, possibly by direct association with actin or spectrin. Mutations in this gene may play a role in postsynaptic congenital myasthenic syndromes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Molecular Weight: 46.1 kDa

NCBI Accession: NP_005046