RRM2B Protein (Myc-DYKDDDDK Tag)
This Recombinant RRM2B protein is expressed in HEK-293 Cells.
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Catalog No. ABIN2731210
$1,112.40
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20 μg
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United States
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Quick Overview for RRM2B Protein (Myc-DYKDDDDK Tag) (ABIN2731210)
Target
See all RRM2B Proteins
RRM2B
(Ribonucleotide Reductase M2 B (TP53 Inducible) (RRM2B))
Protein Type
Recombinant
Origin
Human
Source
HEK-293 Cells
Application
Antibody Production (AbP), Standard (STD)
Purity
> 80 % as determined by SDS-PAGE and Coomassie blue staining
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Purification tag / Conjugate
- This RRM2B protein is labelled with Myc-DYKDDDDK Tag.
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Characteristics
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- Recombinant human RRM2B / P53R2 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- RRM2B (Ribonucleotide Reductase M2 B (TP53 Inducible) (RRM2B))
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Alternative Name
- Rrm2b,p53r2
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Background
- This gene encodes the small subunit of a p53-inducible ribonucleotide reductase. This heterotetrameric enzyme catalyzes the conversion of ribonucleoside diphosphates to deoxyribonucleoside diphosphates. The product of this reaction is necessary for DNA synthesis. Mutations in this gene have been associated with autosomal recessive mitochondrial DNA depletion syndrome, autosomal dominant progressive external ophthalmoplegia-5, and mitochondrial neurogastrointestinal encephalopathy. Alternatively spliced transcript variants have been described.[provided by RefSeq, Feb 2010]
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Molecular Weight
- 40.6 kDa
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NCBI Accession
- NP_056528
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Pathways
- p53 Signaling, Negative Regulation of intrinsic apoptotic Signaling
Target
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