Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

SCARB2 Protein

SCARB2 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2731449
  • Target See all SCARB2 Proteins
    SCARB2 (Scavenger Receptor Class B, Member 2 (SCARB2))
    Protein Type
    Recombinant
    Origin
    • 12
    • 6
    Human
    Source
    • 6
    • 6
    • 4
    • 2
    HEK-293 Cells
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human SCARB2 protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 95 % as determined by SDS-PAGE and Coomassie blue staining
    Endotoxin Level
    < 0.1 EU per μg protein as determined by LAL test
    Top Product
    Discover our top product SCARB2 Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Restrictions
    For Research Use only
  • Buffer
    Lyophilized from a 0.2 μM filtered solution of 20 mM Phosphate buffer, 150 mM NaCl, pH 7.2. Stable for at least 6 months from date of receipt under proper storage and handling conditions.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    SCARB2 (Scavenger Receptor Class B, Member 2 (SCARB2))
    Alternative Name
    Scarb2 (SCARB2 Products)
    Synonyms
    cd36l2 Protein, fi13c07 Protein, chunp6914 Protein, wu:fi13c07 Protein, SCARB2 Protein, scarb2 Protein, AMRF Protein, CD36L2 Protein, EPM4 Protein, HLGP85 Protein, LGP85 Protein, LIMP-2 Protein, LIMPII Protein, SR-BII Protein, 9330185J12Rik Protein, Cd36l2 Protein, MLGP85 Protein, LimpII Protein, scavenger receptor class B, member 2a Protein, scavenger receptor class B member 2 Protein, scavenger receptor class B, member 2 Protein, scarb2a Protein, SCARB2 Protein, scarb2 Protein, Scarb2 Protein
    Background
    The protein encoded by this gene is a type III glycoprotein that is located primarily in limiting membranes of lysosomes and endosomes. Earlier studies in mice and rat suggested that this protein may participate in membrane transportation and the reorganization of endosomal/lysosomal compartment. The protein deficiency in mice was reported to impair cell membrane transport processes and cause pelvic junction obstruction, deafness, and peripheral neuropathy. Further studies in human showed that this protein is a ubiquitously expressed protein and that it is involved in the pathogenesis of HFMD (hand, foot, and mouth disease) caused by enterovirus-71 and possibly by coxsackievirus A16. Mutations in this gene caused an autosomal recessive progressive myoclonic epilepsy-4 (EPM4), also known as action myoclonus-renal failure syndrome (AMRF). Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Feb 2011].
    Molecular Weight
    47.6 kDa
    NCBI Accession
    NP_005497
You are here:
Support