SIRPB1 Protein (Transcript Variant 3) (Myc-DYKDDDDK Tag)
Quick Overview for SIRPB1 Protein (Transcript Variant 3) (Myc-DYKDDDDK Tag) (ABIN2732051)
Target
See all SIRPB1 ProteinsProtein Type
Origin
Source
Application
Purity
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Protein Characteristics
- Transcript Variant 3
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Purification tag / Conjugate
- This SIRPB1 protein is labelled with Myc-DYKDDDDK Tag.
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Characteristics
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- Recombinant human Signal-regulatory protein beta 1 (SIRPB1), transcript variant 3 (transcript variant 3) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- SIRPB1 (Signal-Regulatory Protein beta 1 (SIRPB1))
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Background
- The protein encoded by this gene is a member of the signal-regulatory-protein (SIRP) family, and also belongs to the immunoglobulin superfamily. SIRP family members are receptor-type transmembrane glycoproteins known to be involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. This protein was found to interact with TYROBP/DAP12, a protein bearing immunoreceptor tyrosine-based activation motifs. This protein was also reported to participate in the recruitment of tyrosine kinase SYK. Multiple transcript variants encoding different isoforms have been found for this gene.
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Molecular Weight
- 41 kDa
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NCBI Accession
- NP_001129316
Target
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