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SIRPB1 Protein (His tag)

SIRPB1 Origin: Human Host: Human Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7319458
  • Target See all SIRPB1 Proteins
    SIRPB1 (Signal-Regulatory Protein beta 1 (SIRPB1))
    Protein Type
    Recombinant
    Origin
    • 11
    • 1
    Human
    Source
    • 5
    • 2
    • 2
    • 2
    • 1
    Human Cells
    Purification tag / Conjugate
    This SIRPB1 protein is labelled with His tag.
    Purpose
    Recombinant Human SIRPB1/CD172b Protein (His Tag)
    Sequence
    Glu30-Glu362
    Characteristics
    Recombinant Human SIRPB1 is produced by our Mammalian expression system and the target gene encoding Glu30-Glu362 is expressed with a 6His tag at the C-terminus.
    Purity
    > 95 % as determined by reducing SDS-PAGE.
    Endotoxin Level
    < 1.0 EU per μg as determined by the LAL method.
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    Discover our top product SIRPB1 Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Please refer to the printed manual for detailed information.
    Buffer
    Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
    Storage
    4 °C,-20 °C,-80 °C
    Storage Comment
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target
    SIRPB1 (Signal-Regulatory Protein beta 1 (SIRPB1))
    Alternative Name
    SIRPB1/CD172b (SIRPB1 Products)
    Synonyms
    CD172b Protein, SIRP-BETA-1 Protein, SIRPB1 Protein, SIRPG Protein, signal regulatory protein beta 1 Protein, signal-regulatory protein beta-1 Protein, signal-regulatory protein beta-1 isoform 3 Protein, SIRPB1 Protein, LOC458036 Protein, LOC458430 Protein, LOC485809 Protein, LOC715912 Protein, LOC100458151 Protein
    Background

    Background: Signal-regulatory protein beta-1 (SIRPB1, CD172b) is a member of the signal-regulatory-protein (SIRP) family, and also belongs to the immunoglobulin superfamily. SIRP family members are receptor-type transmembrane glycoproteins known to be involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. This protein was found to interact with TYROBP/DAP12, a protein bearing immunoreceptor tyrosine-based activation motifs. This protein was also reported to participate in the recruitment of tyrosine kinase SYK.

    Synonym: Signal-regulatory protein beta-1, SIRP-beta-1, CD172 antigen-like family member B, CD172b, SIRPB1

    Molecular Weight
    37.4 kDa
    UniProt
    O00241
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