Quick Overview for STAT6 Protein (Myc-DYKDDDDK Tag) (ABIN2732828)
Target
See all STAT6 ProteinsProtein Type
Origin
Source
Application
Purity
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Purification tag / Conjugate
- This STAT6 protein is labelled with Myc-DYKDDDDK Tag.
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Characteristics
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- Recombinant human STAT6 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Signal Transducer and Activator of Transcription 6, Interleukin-4 Induced (STAT6) (AA 1-679) protein (GST tag)
STAT6 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Signal Transducer and Activator of Transcription 6, Interleukin-4 Induced (STAT6) (AA 2-281) protein (His tag)STAT6 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
Signal Transducer and Activator of Transcription 6, Interleukin-4 Induced (STAT6) (AA 627-837) protein (His-IF2DI Tag)STAT6 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- STAT6 (Signal Transducer and Activator of Transcription 6, Interleukin-4 Induced (STAT6))
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Alternative Name
- Stat6
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Background
- The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X(L), which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2) cells, expression of cell surface markers, and class switch of immunoglobulins. Alternative splicing results in multiple transcript variants.[provided by RefSeq, May 2010]
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Molecular Weight
- 94 kDa
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NCBI Accession
- NP_003144
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Pathways
- JAK-STAT Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
Target
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