STUB1 Protein (Myc-DYKDDDDK Tag)

Catalog No. ABIN2732910

This Recombinant STUB1 protein is produced in HEK-293 Cells.

Quick Overview for STUB1 Protein (Myc-DYKDDDDK Tag) (ABIN2732910)

Target: STUB1 (STIP1 Homology and U-Box Containing Protein 1 (STUB1))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Application: Antibody Production (AbP), Standard (STD)

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Product Details

Purification tag / Conjugate: This STUB1 protein is labelled with Myc-DYKDDDDK Tag.

Characteristics:

• Recombinant human STUB1 / CHIP protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: STUB1 (STIP1 Homology and U-Box Containing Protein 1 (STUB1))

Alternative Name: Stub1,chip

Background: This gene encodes a protein containing tetratricopeptide repeat and a U-box that functions as a ubiquitin ligase/cochaperone. The encoded protein binds to and ubiquitinates shock cognate 71 kDa protein (Hspa8) and DNA polymerase beta (Polb), among other targets. Mutations in this gene cause spinocerebellar ataxia, autosomal recessive 16. Alternative splicing results in multiple transcript variants. There is a pseudogene for this gene on chromosome 2.

Molecular Weight: 34.7 kDa

NCBI Accession: NP_005852

Pathways: Regulation of Hormone Metabolic Process, Response to Water Deprivation